Which side effect should clients be monitored for after receiving ondansetron?

Ondansetron is a serotonin receptor antagonist commonly used as an antiemetic to prevent nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. One of the notable side effects associated with ondansetron is gastrointestinal disturbances, including diarrhea. This can occur due to the drug's action on the serotonin receptors in the gastrointestinal tract, leading to increased motility. Therefore, monitoring for diarrhea is essential after the administration of ondansetron, especially in patients who may already be predisposed to gastrointestinal issues.

While insomnia, constipation, and dry mouth may occur with other medications or conditions, they are not well-documented side effects of ondansetron. Insomnia is not a typical effect as ondansetron primarily targets the nausea and vomiting pathways rather than affecting sleep patterns directly. Constipation can be more commonly associated with opioids or other medications that decrease gut motility, and while dry mouth can occur with many medications, it is not specifically highlighted in the context of ondansetron usage.

Overall, monitoring for diarrhea is crucial when patients receive ondansetron, as it can affect patient comfort and potentially lead to further complications if not addressed.