Which antiemetic is a common choice for pregnant women experiencing nausea?

Diphenhydramine is a first-generation antihistamine that is commonly used to alleviate nausea and vomiting in pregnant women. It is recognized for its safety profile during pregnancy and is often recommended for managing motion sickness and nausea due to its sedative effects, which can help provide comfort in early pregnancy when nausea is most prevalent.

While other medications like ondansetron are also used for nausea and vomiting, particularly in cases of chemotherapy-induced nausea, diphenhydramine's historical use and lower risk profile make it a more prevalent choice for pregnant patients. Additionally, aprepitant is more commonly indicated for chemotherapy-related nausea, and meclizine, although effective for motion sickness, does not have the same level of acceptance for pregnancy-related nausea. Therefore, diphenhydramine stands out as a well-accepted choice for managing nausea in pregnant women due to its effectiveness and safety.