What is a common side effect of metoclopramide?

Metoclopramide is an antiemetic and prokinetic agent that is often used to treat nausea and vomiting, as well as to enhance gastrointestinal motility. One of the common side effects associated with metoclopramide is sedation. This sedative effect occurs due to the drug's ability to cross the blood-brain barrier and its antagonistic action on central dopamine receptors, which can lead to drowsiness and decreased alertness.

Patients taking metoclopramide may therefore experience sedation, particularly at higher doses or when combined with other central nervous system depressants. It's important for healthcare providers to inform patients of this potential side effect, as it can affect their ability to perform tasks that require full cognitive function, such as driving.

Other side effects of metoclopramide can include headache, dizziness, and gastrointestinal disturbances, but these are either less common or less pronounced compared to the sedative effects. Understanding these effects can help patients be more prepared for their treatment and manage any adverse reactions.