What complication should a nurse be alert for when administering promethazine to a client with benign prostatic hypertrophy?

When administering promethazine to a client with benign prostatic hypertrophy, it is crucial to be alert for urinary retention as a potential complication. Promethazine is an antihistamine that has anticholinergic properties, which can decrease bladder tone and can lead to difficulty in urination. In clients with benign prostatic hypertrophy, who may already have an obstructed urinary flow due to the enlarged prostate, this effect from promethazine can exacerbate their symptoms, leading to significant urinary retention.

Recognizing this risk is essential for managing the client's condition effectively and ensuring their comfort and safety during the treatment. Monitoring urinary output and assessing for signs of bladder distension can help prevent complications associated with urinary retention in this population.